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Neonatal Platelet Transfusion Threshold Trial

RECRUITING

The objective of the NeoPlaTT trial is to test whether, among extremely preterm infants born at 23 0/7 to 26 6/7 weeks' gestation, a lower platelet transfusion threshold, compared to a higher threshold, improves survival without major or severe bleeding up to 40 0/7 weeks' postmenstrual age (PMA).

I'm interested

ALL
1 hour to 48 hours old
This study is also accepting healthy volunteers

Inclusion Criteria:

  • Gestational age of 23 0/7 to 26 6/7 weeks
  • Postnatal age of < 48 hours

Exclusion Criteria:

  • Comfort care or withdrawal of care planned
  • Neonatal alloimmune thrombocytopenia or suspected/confirmed congenital platelet or bleeding disorder
  • Receipt of platelet transfusion
  • No receipt of Vitamin K
  • Parents/guardian decline consent

PROCEDURE: Higher Platelet Transfusion Threshold, PROCEDURE: Lower Platelet Transfusion Threshold

Thrombocytopenia, Neonatal, Platelet Transfusion, Infant, Newborn, Diseases, Infant, Extremely Low Birth Weight, Infant, Small for Gestational Age, Thrombosis

platelet transfusion, neonatal, thrombosis

Traci Beiersdorfer - traci.beiersdorfer@cchmc.org
NA
NCT06676904
See this study on ClinicalTrials.gov

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