StudyFinder

Use of Hyperpolarized 129Xe MR Lung Imaging in Adults for Calibration

RECRUITING

The goal of this study is to evaluate the usefulness of hyperpolarized (HP) 129Xe (xenon) gas MRI for regional assessment of lung function in a normal population of adults for the purposes of obtaining optimal images through MRI.

I'm interested

ALL
18 years and over
This study is also accepting healthy volunteers

Inclusion Criteria:

  • Adults ages 18 years and older
  • Participant must be able to hold their breath for up to 16 seconds

Exclusion Criteria:

  • History of heart defect
  • Pregnancy or positive pregnancy test
  • History of uncontrolled asthma defined for this study as requiring use of rescue inhaler ≥ 2 times in past month.
  • Symptoms of respiratory infection (loose or productive cough or wheeze), chest tightness, or sinus infection within past week.
  • Baseline oximetry at MRI visit of less than 95% on room air or less than 95% on a previously prescribed dosage of oxygen delivered by nasal cannula.
  • Participant is claustrophobic and unable to tolerate the imaging.
  • Standard MRI exclusions (metal, implants).

DRUG: Hyperpolarized 129 Xenon, DEVICE: MRI

Respiratory Disorders

Respiratory

- jason.woods@cchmc.org
PHASE1
NCT02316379
See this study on ClinicalTrials.gov

Back